Invited talks: Excipients: innovation, regulation, sustainability
| 09:00-09:40 | Overview on sustainability supply of lipid-based excipient Laurent Schubnel, Gattefossé, France |
| 09:40-10:20 | Hilopro - A High Concentration, Low Viscosity , Subcutaneous mAb Delivery Platform Sathyabalan Murugesan, Bhami Research Laboratory, India |
| 10:20-11:00 | Development of excipient monographs from a manufacturers perspective Michael Radius, Lipoid, Germany |
Invited talks: What’s new in nanotechnology and drug targeting?
| 09:00-09:40 | Harnessing Hyaluronic Acid-Conjugates for Improved Glioblastoma Local Immunotherapy Alessio Malfanti, University of Padova, Italy |
| 09:40-10:20 | Langerhans cell targeting via the skin for immune modulation Robert Wawrzinek, Cutanos, Austria |
| 10:20-11:00 | Extracellular vesicles for drug delivery Florence Gazeau, University Paris Diderot, France |
Short talks: Pharmaceutical manufacturing and engineering
| 09:00-09:20 | Downstream processing and in vivo assessment of amorphous Abiraterone Acetate Dispersome® formulations Jumana Merchant, Zerion Pharma A/S, Copenhagen, Denmark |
| 09:20-09:40 | Microdynamic flowability: a novel approach to powder flow analysis David Blanco, University of Helsinki, Finland |
| 09:40-10:00 | Potentialities of lipid-based microspheres and microcapsules obtained by prilling in the field of personalized dosing Claire Delmas, Université Paris Saclay, France |
| 10:00-10:20 | FDmix - a flow-optimized nanoparticle manufacturing platform across all flow ranges Bernhard Bobusch, FDX Fluid Dynamics, Berlin, Germany |
| 10:20-10:40 | Fill finish operation and protein aggregation - what can we learn from a small scale? Milica Stankovic-Brandl, Research Center Pharmaceutical Engineering GmbH, Graz, Austria |
| 10:40-11:00 | Process characterization of freezing and thawing in drug substance bottles – a case study Sarah Peláez, ten23 health, Basel, Switzerland |
Short talks: Advanced Drug Delivery Systems
| 09:00-09:20 | Enkephalins and enkephalinase inhibitors in squalene nanoparticles: a synergistic approach for chronic pain treatment Lucas Prades, University of Paris Saclay, France |
| 09:20-09:40 | Electrospun Nanofibers for Ocular Drug Delivery Finnya Nienau, Martin-Luther-University Halle-Wittenberg, Germany |
| 09:40-10:00 | Expandable gastroretentive system for effective management of diabetes Marco Uboldi, University of Milano, Italy |
| 10:00-10:20 | 3D Printed Dual-Mechanism Drug Delivery Device: Merging Convection-enhanced and Iontophoretic Delivery Methods Hanxiang Li, University College London, United Kingdom |
| 10:20-10:40 | Injectable thermosensitive hydrogel for local and controlled delivery of siRNA polyplexes to ovarian cancer ascites Cristina Casadidio, Univeristy of Utrecht, Univerisity of Camerino, The Netherlands/Italy |
| 10:40-11:00 | Enzyme-responsive NPs: Enhancing endolysins’ ability to eradicate Staphylococcus aureus biofilm Mariana Blanco Massani, University of Innsbruck, Austria |
APV award session
Plenary lecture
| 12:00-13:00 | 3D-Bioprinted cancer models for target discovery, drug development, and personalized therapy Ronit Satchi-Fainaro, Cancer Biology Research Center, Tel Aviv University, Israel |
Invited talks: Innovative manufacturing procedures
| 15:00-15:40 | End-to-end mechanistic and hybrid models of integrated and continuous pharmaceutical manufacturing processes Christian Glaser, Siemens, Austria |
| 15:40-16:20 | 3D Printing for advanced drug delivery Atheer Awad,University of Hertfordshire, UK |
| 16:20-17:00 | Digital pharmaceutics – case studies of how it can support formulation development Martin Kuentz, University of Applied Sciences & Arts Northwestern Switzerland, Switzerland |
Invited talks: Delivery of proteins and peptides
| 15:00-15:40 | Development of inhaled proteins Nathalie Heuzé-Vourc’h, INSERM, Research Center for Respiratory Diseases, France |
| 15:40-16:20 | Stability of antibody drugs on the rocky road from the hospital pharmacy to the oncology ward Hristo Svilenov, University of Ghent, Belgium |
| 16:20-17:00 | The boon and bane of polysorbate 20/80 for protein formulations: current status Patrick Garidel, Boehringer Ingelheim, Germany |
Short talks: Modelling and simulation
| 15:00-15:20 | Molecular dynamics simulations of drugs solubilization into mixed bile salt/phospholipid micelles Fatmegyul Mustan, University of Sofia, Bulgaria |
| 15:20-15:40 | Machine Learning-Assisted System of Models for Optimization of Directly Compressed Tablets Development Processes Mohammad Salehian, University of Strathclyde, Glasgow, United Kingdom |
| 15:40-16:00 | CFD modeling of the hydrodynamics in the flow-through dissolution apparatus (USP 4) Pracha Bunyawanichakul, Srinakharinwirot University, Nakhonnayok, Thailand |
Short talks: Continuous manufacturing
| 16:00-16:20 | Novel Concepts for Processing an Automation of Pharmaceutical End-to-End Manufacturing Lisa Kuchler, Research Center Pharmaceutical Engineering GmbH, Graz, Austria |
| 16:20-16:40 | Integrated continuous twin-screw granulation - process investigation, scale-up and monitoring with artificial neural network-based soft sensors Petra Záhonyi, Budapest University of Technology and Economics, Budapest, Hungary |
| 16:40-17:00 | Evaluating the benefits of continuous wet granulation process, not requiring a subsequent drying step Thorsten Cech, BASF SE, Ludwigshafen, Germany |
Short talks: Nanoparticles and Vesicles I
| 15:00-15:20 | Innovative siRNA-based lipid nanoparticles decorated with PEG alternatives (PNVP and PNMVA) to circumvent dilemma and immunogenicity Manon Berger, University of Liege, Belgium |
| 15:20-15:40 | Ovarian accumulation of nanosized drug delivery systems – what matters? Henrike Lucas, Martin-Luther-University Halle-Wittenberg, Germany |
| 15:40-16:00 | Structural Insights, Uptake Mechanisms and Stability of Nanostructured Lipid Carriers for Advanced Drug Delivery Ramona Jeitler, University of Graz, Austria |
| 16:00-16:20 | Mucosa penetrating peptide functionalized liposomes for local drug delivery to the esophagous Silvia Franzè, University of Milan, Italy |
| 16:20-16:40 | Controlling PEG-b-PTMC Polymersome Size through Microfluidic-Assisted Self-Assembly: Advancing the Understanding of Polymersomes Self-Assembly Mechanisms Angela Mutschler, University of Bordeaux, France |
| 16:40-17:00 | Cholesterol-Modified Hyaluronic Acid Nanogels for Solubility Enhancement and Sustained Release Yoshiyuki Nakagawa, Asahi Kasei Corp., Fuji-Shu, Japan |