Invited talks: Nucleic acid based drugs and vaccines

09:00-09:40 Targeted lipid nanoparticles with RNAs are going beyond the liver: from vaccines to therapeutic genome editing
Dan Peer, University of Tel Aviv, Israel
09:40-10:20 mRNA drugs: an industrial perspective
Carla Atallah, Sanofi, France
10:20-11:00 Extrahepatic delivery of siRNA, a theranostic approach
Ick Chan Kwon, Institute of Science and Technology, Korea University, Korea

Invited talks: Local drug delivery

09:00-09:40 Drug targeting to the esophagus
Christoph Rosenbaum, University of Greifswald, Germany
09:40-10:20 Recent advances in drug-releasing vaginal rings
Karl Malcolm, Queen‘s University of Belfast, UK
10:20-10:40 Nanofibers as a local delivery system for vaginal probiotics
Spase Stojanov, Institute of Jožef Stefan, Ljubljana, Slovenia
10:40-11:00 Contact lenses that self-generate gold nanoparticles for light filters and photothermal therapy
Carmen Alvarez-Lorenzo, University of Santiago de Compostela, Spain

Short talks: 2D/3D printing

09:00-09:20 Development of a 3D-printed polypill for breast cancer management
Lucas Denis, Gustave Roussy Cancer Campus, Villejuif, France
09:20-09:40 Free-d Molding - Every Idea Deserves a Prototype
Daniel Treffer, MeltPrep GmbH, Graz, Austria
09:40-10:00 Development of an enteric (delayed-release) formulation for semi-solid extrusion 3D printing
Kristiine Roostar, University of Tartu, Estonia
10:00-10:20 Combining two different 3D printing processes for the production of Donepezil-coated microneedle arrays
Paraskevi Kyriaki Monou, Aristotle University of Thessaloniki, Greece
10:20-10:40 Development of 3D printed bioadhesive films containing different types of propolis extractive solutions
Marcos Luciano Bruschi, State University of Maringa, Brazil
10:40-11:00 Direct extrusion of cyclodextrin-based powders to produce customized pharmaceutical dosage forms by 3D printing
Nunzio Denora, University of Bari Aldo Moro, Italy

Short talks: Oral Delivery

09:00-09:20 Unexpected release behavior of copovidone-based ASDs
Dominik Borrmann, TU Dortmund University, Germany
09:20-09:40 Solubility enhancement of PROTACs via Spray drying with Polyvinyl alcohol
Lena Mareczek, Merck Life Science KGaA, Darmstadt, Germany
09:40-10:00 Exploring oral device-based in situ amorphization of poorly soluble small molecule drugs
Maria Pereverzina, University of Copenhagen, Denmark

Short talks: In vitro and In vivo assessment of oral dosage forms

10:00-10:20 Visualisation of the “Magenstrasse” using Realtime Magnetic Resonance Imaging
Linus Großmann, University of Greifswald, Germany
10:20-10:40 Device for simultaneous dissolution and permeation measurement
David Zuza, University of Chemistry and Technology of Prague, Czech Republic
10:40-11:00 Impact of stabilizers in solid nanocrystal formulations on particle size and dispersion behavior in biorelevant media
Julius Sundermann, Abbvie Deutschland GmbH & Co. KG, Ludwigshafen, Germany

SITELF award session

Plenary lecture

12:00-13:00 Hyaluronic acid in targeted drug delivery. What we understand, what we do not understand, and what we do not even know we do not understand
Nicola Tirelli, Italian Institute of Technology, Italy

Invited talks: Patient-focused drug delivery

15:00-15:40 Why and how introduce patient centered approaches in pharmaceutical product development
Leonie Wagner, Hoffmann-La Roche, Switzerland
15:40-16:20 Development of a research program for qualified methods to assess „acceptability“
Sven Stegemann, Leibniz JointLab fiT, Germany
16:20-16:40 Automated Medication Management: Empowering Adherence through “Robo-Pharmacist” Technology
Erik Sonntag, University of Chemistry and Technology of Prague, Czech Republic
16:40-17:00 3D printing of personalized medicines in a hospital setting for children affected by rare metabolic disorders
Paola Carou-Senra, University of Santiago de Compostela, Spain

Invited talks: Bio-barriers and alternative routes of administration

15:00-15:40 Oral delivery strategies based on nanoparticles for biologics
Juan M. Irache, University of Navarra, Spain
15:40-16:20 The impact of lung epithelial transporters on pulmonary drug delivery
Carsten Ehrhardt, Trinity College Dublin, Ireland
16:20-17:00 Nasal delivery for effects in the brain: it works
Ben Forbes, Kings College London, United Kingdom

Short talks: Controlled drug delivery

15:00-15:20 Subcutaneous long-acting risperidone implants for schizophrenia treatment
Eneko Larraneta, Queen´s University Belfast, United Kingdom
15:20-15:40 HA-Glucose, a hyaluronan-based hydrogel to feed mesenchymal stem cells delivered for osteoarthritis therapy
Paula Gonzalez Fernandez, University of Geneva, Switzerland
15:40-16:00 Thermosensitive in situ gelling poloxamers/hyaluronic acid gels for ocular delivery
Laura Mayol, University of Naples Federico II, Italy

Short talks: Buccal and nasal and pulmonary delivery

16:00-16:20 Intranasal nose-to-brain delivery of a monoclonal antibody with a controlled release drug delivery system: proof-of-concept and pharmacokinetic studies in mini pigs
Katharina Schindowski Zimmermann, Biberach University of Applied Sciences, Germany
16:20-16:40 Combining microneedles with electrospun mucoadhesive patches to improve buccal transmucosal drug delivery
Cerys Evans, University of Sheffield, United Kingdom
16:40-17:00 RNhale - a dry powder platform technology for Pulmonary RNA delivery
Leonie Deßloch, Ludwig Maximilians University of Munch, Germany

Short talks: Parenteral Delivery

15:00-15:20 Release of insulins using IVR cartridge as model for subcutaneous tissue: medium effects and albumin binding
Jesper Ostergaard, University of Copenhagen, Denmark
15:20-15:40 Novel thermo-sensitive oleogels as long acting injectables for the delivery of hydrophilic drugs
Valeria Tamburrini, University of East Anglia, United Kingdom
15:40-16:00 Exploring bottom-up approaches towards long-acting injectable suspensions
Sarah Hudson, University of Limerick, Ireland

Short talks: Protein formulations

16:00-16:20 A versatile platform for orthogonal analysis of protein physical stability in multiwell plates
Michaela Cohrs, University of Ghent, Belgium
16:20-16:40 Single-Step Freeze-Drying of Protein Formulations
Elena Richert, Ludwig-Maximilians-University of Munich, Germany
16:40-17:00 The Viscosity Reduction Platform: Enabling High-concentration and Low-viscosity Protein Formulations
Can Araman, Merck Life Science KGaA, Darmstadt, Germany