Invited talks incl. Q&A: Formulation issues for biotech drugs

08:45-09:35 Pellet freeze-drying of biopharmaceuticals
Stefan Schneid, Bayer, Wuppertal, Germany
09:35-09:50 Please stay my dear: Interfacial adsorption as driving force for protein particle formation during peristaltic pumping
Natalie Deiringer, University of Munich, Germany
09:50-10:05 Creating Highest Quality L yophilisates With Low Oxygen and Water Content by Smart Polymer Packaging
Nicole Härdter, University of Munich, Germany
10:05-10:25 Question and answer session
10:25-11:15 Biologics drug product development: challenges at the interface of formulation, primary packaging and application
Susanne Jörg, Lonza AG, Basel, Switzerland

Invited talks incl. Q&A: Localised drug delivery

08:45-09:35 Jumping to the brain: Tailored nanomedicines
Giovanni Tosi, University of Modena and Reggio Emilia, Italy
09:35-09:50 Development of a dissolution method for dosage forms administered into subtenon space
Tobias Auel, Univeristy of Greifswald, Germany
09:50-10:05 Impact of the in vitro release set-up on drug release from PLGA implants
Celine Bassand, University of Lille, France
10:05-10:25 Question and answer session
10:25-11:15 Inhaled chemotherapy: A new modality for lung cancer treatment?
Nathalie Wauthoz, Université Libre de Bruxelles, Belgium

Short talks: Nanotechnology

08:45-09:00 Heterotelechelic polymer prodrug nanoparticles for imaging and combination theraphy
Julien Nicolas, University Paris-Sud, France
09:00-09:15 Enhanced performance of lipid nanocapsule formulations of NIR-emitting conjugated polymers for optical and photoacoustic imaging
speaker to be confirmed
09:15-09:35 Question and answer session
09:35-09:50 Antiangiogenic folate-targeted nanoparticles for docetaxel delivery in ovarian cancer
Claudia Conte, University of Naples Federico II, Italy
09:50-10:05 Cellular and subcellular targeting of TRAP1 as a new therapeutic approach for cancer treatment
Clelia Mathieu, Institute Galien - Paris Sud, France
10:05-10:25 Question and answer session
10:25-10:40 Effects of cytokines release in tissue regeneration and cancer treatments
Slivia Pisani, University of Pavia, Italy
10:40-10:55 Bacterial membrane vesicles as novel treatment avenue for intracellular infections
Gregor Fuhrmann, HIPS, Saarbrücken, Germany
10:55-11:15 Question and answer session

Short talks: Continuous manufacturing / Modeling and simulation

08:45-09:00 Characterization of a Continuous Small-Scale Solid-Liquid Separator for Filtration, Washing, and Drying of Pharmaceutical Suspensions
Claas Steenweg, University of Dortmund, Germany
09:00-09:15 Coninuous production of cyclodextrin-based reconstitution powder from aqueous solution using scaled-up electrospinning
Panna Vass, Budapest University of Technology and Economics, Hungary
09:15-09:35 Question and answer session
09:35-09:50 An in-silico workflow for designing a continuous mixing process with DEM simulations
Peter Toson, RCPE, Graz, Austria
09:50-10:05 Visualization of solvent effects on crystal surfaces by chemical force mapping - a combined experimental and simulation approach
Mikkel Herzberg, University of Copenhagen, Denmark
10:05-10:25 Question and answer session
10:25-10:40 Predicting crystal breakage in pharmaceutical agitated dryers
Francois Hallac, University of Leeds, UK
10:40-10:55 Dissolution and re-crystallization of supersaturated indomethacin solutions
Andreas Danzer, University of Dortmund, Germany
10:55-11:15 Question and answer session

APV award session

11:45-12:15 to be announced
To be determined

Plenary lecture incl. Q&A

Invited talk

12:15-13:15 Pharmacomicrobiomics: drugs meet the human microbiome
Christine Moissl-Eichinger, Medical University of Graz, Austria

Invited talks incl. Q&A: Oral drug delivery

14:45-15:35 Hydrophobic ion pairs: a game-changing approach for delivery of BCS class 3 drugs
Andreas Bernkop-Schnürch, Faculty of Chemistry and Pharmacy, University of Innsbruck, Austria
15:35-16:25 Biological barriers to oral delivery of macromolecules
Caitriona O‘Driscoll, School of Pharmacy, University of Cork, Ireland
16:25-17:15 The virtual patient and the in-silico design of solid dosage forms
Hans Leuenberger, College of Pharmcy, University of Florida, Lake Nona medical campus, Orlando, FL, USA

Invited talks incl. Q&A: Amorphous drug delivery systems

14:45-15:35 Hybrid mixtures: A perspective on amorphous solid dispersions in food applications
Lennart Fries, Nestlé Research Center, Vevey, Switzerland
15:35-16:25 Rational selection of Amorphous Solid Dispersion (ASD) Compositions for Improving Drug Candidate Bio-performance
David Lyon, Lonza, USA
16:25-17:15 The variability of the amorphous state in relation to processing
Marc Descamps, University of Lille, France

Short talks: 2D- and 3D-printing

14:45-15:00 Direct powder extrusion 3D-printing: novel technology for manufacturing amorphous solid dispersions
Alvaro Goyanes, FabRx, London, UK
15:00-15:15 Semi-solid extrusion and 3D-printing: successful duo for the production of personalized gastro-retentive formulations
Paola Russo, University of Salerno, Fisciano, Italy
15:15-15:35 Question and answer session
15:35-15:50 Selective Laser Sintering of Solid Oral Dosage Forms with Copovidone and Paracetamol Using a CO2 Laser
Yanis Abdelhamid Gueche, University of Montpellier, France
15:50-16:05 Direct-ink writing of implantable hybrid PCL/PEO drug delivery systems
Se Hun Chung, University College London, UK
16:05-16:25 Question and answer session
16:25-16:40 Investigations on inkjet printed metoprolol tartrate orodispersible films for paediatric application
Olga Kiefer, University of Düsseldorf, Germany
16:40-16:55 Traceable personalized oral dosage forms containing cannabinoids
Natalia Genina, Abo Akademi University, Finland
16:55-17:15 Question and answer session

Short talks: Skin delivery and protein formulations

14:45-15:00 A new approach to predict in vitro-in vivo correlation for transdermal therapeutic systems
René Rietscher, LTS Lohmann Therapie-Systeme, Andernach, Germany
15:00-15:15 Proliposomes for the production of deformable liposomes containing drug micelles
Silvia Franze, Univeristy of Milan, Italy
15:15-15:35 Question and answer session
15:35-15:50 EPR study of effect of ascorbic acid on hair and feather samples in relation to eumelanins and pheomelanins
Michael Lawson, University of Bratislava, Slovakia
15:50-16:05 α-relaxation studies to improve long term stability of lyophilized products from a thermodynamical point of view
Sebastial Groel, Univeristy of Munich, Germany
16:05-16:25 Question and answer session
16:25-16:40 Continuous alternative to freeze-drying: solid formulation of a monoclonal antibody using high-speed electrospinning
Júlia Domján, Budapest University of Technology and Economics, Hungary
16:40-16:55 A holistic approach to develop a spray-drying method for CXCL8
Sonja Hartl, RCPE, Graz, Austria
16:55-17:15 Question and answer session