
Invited talks: In silico simulation for manufacturing processes
09:00-09:40 | Digitalization in pharmaceutical product and process design: from advanced simulations to virtual drug product development Johannes Khinast, Graz University of Technology, Austria |
09:40-10:20 | Digital Process Design Sean Bermingham, Process System Enterprise (PSE), London, United Kingdom |
10:20-11:00 | Modelling and simulation of fluid-bed processes Stefan Heinrich, Hamburg University of Technology, Germany |
Invited talks: Nanofabrication technologies
09:00-09:40 | Novel manufacturing for healthcare: microbubbles, particles, capsules and fibres Mohan Edirisinghe, Biomaterials Processing Laboratory, Department Mechanical Engineering, University College London, United Kingdom |
09:40-10:20 | Advances in electrospinning Nalin de Silva, Department of Chemistry, University of Colombo, Sri Lanka |
10:20-11:00 | Advanced in vitro lung-on-chip platforms for inhalation assays Josue Sznitman, Department of Biomedical Engineering, Israel Institute of Technology, Haifa, Israel |
Short talks: Processing and PAT
09:00-09:20 | to be determind to be determind |
09:20-09:40 | Production and downstream-processing of API-nanosuspensions Arno Kwade, Technical University of Braunschweig, Germany |
09:40-10:00 | Improving particle size distributions in a conical mill through new impeller air flow optimization comparisons utilizing computational fluid dynamics (CFD) analysis and empirical DoE Wilf Sanguesa, Quadro Engineering, Ontario, Canada |
10:00-10:20 | Process control of high shear melt granulation processes by inline particle size analysis Gerd Kutz, OWL University of Applied Sciences and Arts, Detmold, Germany |
10:20-10:40 | Designing an at-line PAT tool - a fluid bed coating case study Jaspreet Arora, Lonza Pharma and Biotech, Bend, USA [TBC] |
10:40-11:00 | NIR as an in-line PAT tool to study desorption kinetics in spin freeze-dried formulations Laurens Leys, Ghent University, Belgium |
Short talks: Gene delivery and ATMP
09:00-09:20 | Formulation development to stabilize viral vectors Sabine Hauck, Leukocare, Munich, Germany |
09:20-09:40 | to be determind to be determind |
09:40-10:00 | Anti-EGFR nanovector of siRNA - a theranostic tool for triple negative breast cancer active targeting Phuoc Vinh Nguyen, Tours University, France |
10:00-10:20 | siRNA in lung slices: knocking down fibrosis? Mitchel Ruigrok, University of Groningen, The Netherlands |
10:20-10:40 | to be determind to be determind |
10:40-11:00 | MSC extracellular vesicles for treatment of alpha-1-antitrypsin deficiency pulmonary diseases Elia Bari, University of Pavia, Italy |
ADRITELF award session
11:30-12:00 | International ADRITELF Award 2020 To be determined in March 2020 |
Plenary lecture
Invited talk
12:00-13:00 | Oral drug delivery systems: from irrelevance to top-selling products and ongoing challenges Andrea Gazzaniga, Biopharmaceuticals and Pharmaceutical Technology Laboratory, University of Milan, Italy |
Invited talks: Dermal and transdermal delivery
15:00-15:40 | Skin permeation from pickering emulsions Marie-Alexandrine Bolzinger, Claude Bernard University Lyon, France |
15:40-16:20 | Microarray patches for high-dose drug delivery: targeting global healthcare challenges Ryan F. Donnelly, School of Pharmacy, Queen's University Belfast, United Kingdom |
16:20-17:00 | Improved vaccine immunogenicity through microneedle delivery Michael Schrader, Vaxess, Boston, MA, USA |
Invited talks: Continuous manufacturing
15:00-15:40 | Process development of the future: fully automated DoE process analysis in an integrated continuous manufacturing plant for solid oral dosage forms Victoria Pauli, Novartis, Basel, Switzerland |
15:40-16:20 | Pfizer´s "continuous" journey - Implementing continuous manufacturing into a factory for solid dosage forms Clemens Stief, Pfizer, Freiburg, Germany |
16:20-17:00 | Continuous manufacturing of solid dosage forms; opportunities and controversies Kendal Pitt, GlaxoSmithKline, Ware, United Kingdom |
Short talks: Advanced drug delivery
15:00-15:20 | Repurposing of cationic amphiphiles to promote cytosolic RNA delivery Koen Raemdonck, Ghent University, Belgium |
15:20-15:40 | to be determind to be determind |
15:40-16:00 | Intravitreal administration of bevacizumab: optimization of freeze-dried solid matrices Eleonora Terreni, University of Pisa, Italy [TBC] |
16:00-16:20 | FRET as a tool for monitoring polyplex assembly and for tracking its cellular fate Lorenz Isert, LMU Munich, Germany |
16:20-16:40 | A novel polyethlyene glycol-based linker platform for the development of hydrophilic antibody-drug conjugates Gianfranco Pasut, University of Padova, Italy |
16:40-17:00 | to be determind to be determind |
Short talks: Oral drug delivery / Pediatric formulations
15:00-15:20 | to be determind to be determind |
15:20-15:40 | X-ray imaging of micorcontainers used for oral drug delivery Rolf B. Kjeldsen, Technical Univeristy of Denmark, Lyngby, Denmark |
15:40-16:00 | Controlled permeability enhancement with short peptide inhibitors of protein kinase C zeta Joel Brunner, University of Geneva, Switzerland |
16:00-16:20 | A toolbox for mimicking gastrointestinal conditions in children: S(imulated) P(ediatric) B(reakfast) M(edia) for addressing the variability of gastric contents after typical paediatric breakfasts Lisa Freerks, University of Greifswald, Germany [TBC] |
16:20-16:40 | Design and evaluation of self-emulsifying drug delivery system for pediatric use Xiaona Liu, University of Copenhagen, Denmark |
16:40-17:00 | Acceptability of antibiotics in pediatrics: findings from an international observational study Thibault Vallet, ClinSearch, Malakoff, France |